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产品名称:重组SARS-CoV-2 S1-CTD(8His-Flag标签)
英文名称:Recombinant SARS-CoV-2 S1 Protein CTD (N-8His-Flag)
产品货号:JN2096
产品规格:1mg
本制品由哺乳动物表达系统制备,目的基因编码表达SARS-CoV-2 S1蛋白CTD,N端含8*His-Flag标签,用作免疫原或标准品。
技术指标:
Accession#:QHD43416.1
分子量:17.3kDa
实测分子量:28-50kDa(还原条件下)
纯度:>95%(还原性SDS-PAGE)
纯化方式:亲和色谱法
贮存液:PBS,pH7.4,0.2μm过滤
保存条件:-20℃。
背景资料:
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation,apoptosis,cancer development and progression,and the innate immune response.Known receptors bind S1 are ACE2,angiotensin-converting enzyme 2,DPP4,CEACAM etc.The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process.Most notable is severe acute respiratory syndrome (SARS).The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion.It is also a major immunogen and a target for entry inhibitors.It"s been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor.The spike protein is a large type I transmembrane protein containing two subunits,S1 and S2.S1 mainly contains a receptor binding domain (RBD),which is responsible for recognizing the cell surface receptor.S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses,as well as protective immunity.
根据您的关注的
重组SARS-CoV-2 S1-CTD(8His-Flag标签)(>95%),Recombinant SARS-CoV-2 S1 Protein CTD (N-8His-Flag),重组新型冠状病毒S1-CTD,重组8His-Flag标签,重组SARS-CoV-2 S1 Protein CTD (N-8His-Flag),重组SARS-CoV-2 S1-CTD,重组新冠病毒S1-CTD,您可能还对以下产品有需求:
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关注
重组SARS-CoV-2 S1-CTD(8His-Flag标签)(>95%),Recombinant SARS-CoV-2 S1 Protein CTD (N-8His-Flag),重组新型冠状病毒S1-CTD,重组8His-Flag标签,重组SARS-CoV-2 S1 Protein CTD (N-8His-Flag),重组SARS-CoV-2 S1-CTD,重组新冠病毒S1-CTD的同时,为您推荐更多您可能感兴趣的产品:
名称:重组人β-NGF(神经生长因子)
货号:JN0221
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Glu19-Ala241表达纯化而来。
NGF(with pro peptide)质量控制:>95%(还原性SDS-PAGE)。
NGF(with pro peptide)制剂:冻干品
NGF(with pro peptide)保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
NGF(with pro peptide)复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于NGF(with pro peptide):
The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
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