重组SARS-CoV-2 S1蛋白(mFc标签)(＞95%)

特别提示：包括重组SARS-CoV-2 S1蛋白(mFc标签)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组SARS-CoV-2 S1蛋白(mFc标签)
英文名称：Recombinant SARS-CoV-2 S1 Protein
产品货号：JN2080
产品规格：50μg|500μg|1mg

本制品由哺乳动物表达系统制备，目的基因编码表达SARS-CoV-2 S1 Protein(Gln14-Arg685)，C端带有一个mFc标签，用作免疫原或标准品。

Accession#：QHD43416.1
分子量：101.3kDa
实测分子量：130-160kDa（还原条件下）
纯度：＞95%（还原性SDS-PAGE）
纯化方式：亲和色谱法
贮存液：PBS，pH7.4，0.2μm过滤
保存条件：-20℃。

生物活性：

Immobilized Human ACE-2-Fc(CAT#JN2061) at 10μg/ml (100μl/well) can bind SARS-CoV-2 S1 Protein-mFc (Cat#JN2080).The ED₅₀of SARS-CoV-2 S1 Protein-mFc (Cat#JN2080) is 190ng/mL.

背景资料：
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation,apoptosis,cancer development and progression,and the innate immune response.Known receptors bind S1 are ACE2,angiotensin-converting enzyme 2,DPP4,CEACAM etc..The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process.Most notable is severe acute respiratory syndrome (SARS).The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion.It is also a major immunogen and a target for entry inhibitors.It"s been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor.The spike protein is a large type I transmembrane protein containing two subunits,S1 and S2.S1 mainly contains a receptor binding domain (RBD),which is responsible for recognizing the cell surface receptor.S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses,as well as protective immunity.

根据您的关注的重组SARS-CoV-2 S1蛋白(mFc标签)(＞95%)，重组SARS-CoV-2 S1蛋白，重组新冠病毒S1蛋白，Recombinant SARS-CoV-2 S1 Protein，重组新型冠状病毒S1蛋白，重组mFc标签，重组SARS-CoV-2 S1 Protein，您可能还对以下产品有需求：


JN0398 重组人白介素17受体A( IL-17RA) 10μg|50μg|500μg|1mg
JN0561 重组人AZGP1 10μg|50μg|500μg|1mg
JN0763 重组人MECR(线粒体反式烯脂酰-CoA还原酶) 10μg|50μg|500μg|1mg
JN0833 重组人BCAN(短蛋白聚糖核心蛋白) 10μg|50μg|500μg|1mg
JN0846 重组人低密度脂蛋白受体(LDLR) 10μg|50μg|500μg|1mg
JN0891 重组人谷胱甘肽S-转移酶ζ1(MAAI) 10μg|50μg|500μg|1mg
JN1017 重组人氯离子胞内通道蛋白1(CLIC1) 10μg|50μg|500μg|1mg

关注重组SARS-CoV-2 S1蛋白(mFc标签)(＞95%)，重组SARS-CoV-2 S1蛋白，重组新冠病毒S1蛋白，Recombinant SARS-CoV-2 S1 Protein，重组新型冠状病毒S1蛋白，重组mFc标签，重组SARS-CoV-2 S1 Protein的同时，为您推荐更多您可能感兴趣的产品：



名称：重组人FGFRL1(成纤维细胞生长因子受体样因子1)(带His标签)
货号：JN0236
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Ala25-Pro378在C端含有His标签。

FGFRL1质量控制：＞95%(还原性SDS-PAGE)。

FGFRL1制剂：冻干品

FGFRL1保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

FGFRL1复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于FGFRL1：
Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 Ig-like C2-type domains, a 21 amino acid transmembrane segment, and a 134 amino acid cytoplasmic domain. FGFR1 expressed in various tissues, preferentially in cartilaginous tissues and pancreas. It highly expressed in the liver, kidney, heart, brain and skeletal muscle, weakly expressed in the lung, small intestine and spleen. FGFRL1 has a negative effect on cell proliferation.

北京百奥莱博科技有限公司一家专注于生命科学研究领域的生物技术公司，坚持“质量至上，服务为本，全心全意助力生命科学”的理念，为广大用于提供稳定、可靠、专业的产品和服务支持，产品线包括分子生物学，细胞生物学，免疫检测，抗体，重组蛋白，血液制品等系列。“忙忙碌碌的平凡，铸就事业的不凡”。让我们携起手来，共同创造生命科学的蓬勃发展。