特别提示:包括兔抗人EGF单抗在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:兔抗人EGF单抗
英文名称:Anti-human EGF Antibody
产品货号:Q50003
产品规格:50μL|100μL
交叉反应:人
特异性:人EGF
宿主:兔
克隆性:单克隆
纯化方式:蛋白A纯化
制剂:液体
保存条件:-20℃,避免反复冻融
蛋白全称:epidermal growth factor
推荐应用:
应用 |
推荐稀释比例 |
ELISA |
1:5000-1:10000 |
背景资料:
EGF is the founding member of the EGF-family of proteins.Members of this protein family have highly similar structural and functional characteristics.EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats.Human EGF is a 645-Da protein with 53 amino acid residues and three intramolecular disulfide bonds.As a low-molecular-weight polypeptide,EGF was first purified from the mouse submandibular gland,but since then it was found in many human tissues including submandibular gland,parotid gland.It can also be found in human platelets,macrophages,urine,saliva,milk,and plasma.EGF is a growth factor that stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture.It results in cellular proliferation,differentiation,and survival.Salivary EGF,which seems also regulated by dietary inorganic iodine,also plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity.EGF acts by binding with high affinity to epidermal growth factor receptor on the cell surface and stimulating the intrinsic protein-tyrosine kinase activity of the receptor.The tyrosine kinase activity,in turn,initiates a signal transduction cascade that results in a variety of biochemical changes within the cell - a rise in intracellular calcium levels,increased glycolysis and protein synthesis,and increases in the expression of certain genes including the gene for EGFR - that ultimately lead to DNA synthesis and cell proliferation.
根据您的关注的
兔抗人EGF单抗,兔抗人表皮生长因子单克隆抗体,您可能还对以下产品有需求:
名称:磷酸化蛋白激酶AKT1抗体
货号:K10704
规格:0.1ml
宿主物种:兔
交叉反应:人,小鼠,大鼠,鸡,狗,猪,奶牛,兔,绵羊
克隆类型:多克隆
分 子 量:56kDa
浓 度:1mg/1ml
亚 型:IgG
细胞定位:细胞核 细胞浆 细胞膜
免 疫 原:KLH conjugated synthesised phosphopeptide derived from human
纯化方法:蛋白A亲和纯化
产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
尚未测试其他应用;
实际稀释浓度可根据用户的具体用途决定。
储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件:4℃运输,-20℃保存,避免反复冻融
应用领域:肿瘤 细胞生物 信号转导 细胞凋亡 转录调节因子
名称:磷酸化蛋白激酶AKT1抗体
货号:K10770
规格:0.1ml
宿主物种:兔
交叉反应:人,小鼠,大鼠,鸡,狗
克隆类型:多克隆
分 子 量:60kDa
浓 度:1mg/1ml
亚 型:IgG
细胞定位:细胞核 细胞浆 细胞膜
免 疫 原:KLH conjugated synthesised phosphopeptide derived from human
纯化方法:蛋白A亲和纯化
产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
尚未测试其他应用;
实际稀释浓度可根据用户的具体用途决定。
储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件:4℃运输,-20℃保存,避免反复冻融
应用领域:肿瘤 细胞生物 信号转导 激酶和磷酸酶 新陈代谢 表观遗传学
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