全身体积描记系统

产品描述 

塔望科技研发的全身体积描记系统（whole-body plethysmograph，WBP）可对清醒自由活动动物呼吸参数进行测量，如呼吸频率，潮气量，气道高反应性测试（Airway hyperresponsiveness，AHR）等。测试过程中，动物可以处于清醒自由状态，避免了创伤性气管切开及麻醉的影响，使实验过程更加简便，用于呼吸系统模型动物对药物等反应性研究，呼吸性药物的药理和毒理学研究，特别适合于大批量动物快速初筛试验，适合长期跟踪研究和重复性筛查。

产品特点

· 不需要做手术，操作简单

· 可多通道同时监测

· 可在动物在自然状态下呼吸的研究以及长期跟踪实验，适合进行药物初筛

· 具有药物气溶胶雾化模块

· 具有自动标定功能

· 具有饮水口和食物口，可进行长期连续监测

· 可选配测量心电、血压、体温、心率等指标，可与植入式遥测设备联合使用

· 具有分析软件，数据可保存至excel或txt格式

可选配的功能模块：

· 同步视频监测：同步的视频录像文件

· 咳嗽检测：通过软件自动监测咳嗽事件

· 其它生理指标测量：可在麻醉或清醒状态下测量心电、血压、体温、心率等指标，可与植入式遥测设备联合使用

检测参数

Ti：吸气时间（s）

Te：呼气时间（s）

PIF：最大吸气流速（ml/s）

PEF：最大呼气流速（ml/s）

Volbal：吸气时间/呼气时间

F：呼吸频率（次/min）

Vt：潮气量（ml）

Mv：分钟通气量（ml）

AV：累积体积（ml）

EF50：呼出50%气量时对应的呼气流速（ml/s）

EIP：吸气峰值压力（仅在侵入式法测量时有效）

EEP：呼气峰值压力（仅在侵入式法测量时有效）

TR：松弛时间

PenH：增强呼气间歇（enhanced pause）

Rpef：相对时间

适用领域

• 各种呼吸疾病研究，如：哮喘、肺纤维化、肺损伤、ARDS、肺癌等

• 安全药理：药物对呼吸系统的影响

• 睡眠呼吸：监测动物低通气、阻塞性呼吸暂停等

• 环境毒理：环境污染物对动物呼吸的影响

• 吸入式毒理：染毒物质对呼吸系统的毒性影响

• 高原医学：高原环境对呼吸系统的影响

• 其它需要对呼吸参数评价的场合

型号说明

相关文献

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[25]Biological Hyperthermia-Inducing Nanoparticles for Specific Remodeling of the Extracellular Matrix Microenvironment Enhance Pro-Apoptotic Therapy in Fibrosis。Jinru Zhang, Keqin Ji, Yuanmeng Ning, Lingna Sun, Mingrui Fan, Chunjie Shu, Ziqi Zhang, Tianyu Tu, Jingyun Cao, Feng Gao, and Yanzuo Chen  ACS Nano 2023 17 (11), 10113-10128   DOI: 10.1021/acsnano.2c12831

[26]Yize Yin,Chaohui Mu,Jiahui Wang,Yixuan Wang, Wenmin Hu,Wenjing Zhu,Xinjuan Yu,Wanming Hao,Yuxin Zheng, Qinghai Li, Wei Han. CXCL17 Attenuates Diesel Exhaust Emissions Exposure-Induced Lung Damage by Regulating Macrophage Function,[J]2023-07-26,DOI: 10.3390/toxics11080646

[27]Gao-Xiang Wang,Jie Zhou,You-Mou Chen,Liang-Dong Xu,Shan-Ming Tao,Jia Ma,Ye-Han Sun,Ming-Sheng Wu,Zheng-Wei Chen,Yong-Fu Zhu,Ming-Ran Xie,Mechanism of electroacupuncture at acupoints of the lung meridian through PKA/PKC regulation of TRPV1 in chronic cough after lung surgery in guinea pigs,[J]PMC 2023 Apr 28; 15(4): 1848–1860.DOI:10.21037/jtd-23-409

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​​​​​​​[29]Yimeng Shu, Ming Ma, Xiaoxia Pan, Muhammad Shafiq, Huizhu Yu, Hangrong Chen,Cobalt protoporphyrin-induced nano-self-assembly for CT imaging, magnetic-guidance, and antioxidative protection of stem cells in pulmonary fibrosis treatment,[J]Bioactive Materials,Volume 21,2023,Pages 129-141,ISSN 2452-199X
 

*我公司可以根据客户的特殊应用、特殊需求提供功能定制服务，也可以提供相关的实验服务，详情请来电咨询。

     响应“中国制造2025”的战略号召，2018 年成立于上海交科科创园内，是一家生物医药实验设备开发销售的高新技术企业。我司致力于在该领域打破国外产品垄断,树立起值得骄傲的中国制造品牌。
     公司目前的产品线包括:疾病造模设备、动物呼吸检测、高压低/高氧控制、麻醉机、能量代谢、脊髓/脑损伤仪、宠医医疗器械等，所有产品均为自主研发，同时塔望科技融合生命科学、医学、IT、 电子、机械等领域先进技术，为客户提供量身定制方案，满足个性化的需求。
     我们在生命科学、医药研发等领域也在迅速追赶、逐渐超越欧美国家。目前落后于西方的生命科学仪器设备研发制造业也必然在中国创新创造的大背景下，迎来新的超越。这是时代给我们的机会。匠心筑梦，诚信筑塔，严谨求实，展望将来。塔望科技坚守工匠精神，用心做好每一件产品。我们将在这个瞬息万变的黄金时代，为本领域科学家提供值得骄傲和信赖的产品。