beta-淀粉样多肽-40

beta-淀粉样多肽-40

Amyloid β-Protein (1-40)

Cat#: 107P33

序列（三字母）：H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH

序列（单字母）：DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV

类似名：Aβ40

分子式：C₁₉₄H₂₉₅N₅₃O₅₈S

分子量：4329.86

CAS#：131438-79-4

合成方法：Synthetic

存储条件：-20 ± 5 °C

应用：Alzheimer's Disease

描述：Amyloid β-peptide (1-40) showed both neurotrophic and neurotoxic effects in dependence on the neuronal age and the concentration of the β-protein. Aβ 1-40 has been used as well as Aβ 1-42 to detect amyloid β-protein multimers in the cerebrospinal fluid of Alzheimer's disease patients. The sequence of H-1194 corresponds to the human, bovine, canine, feline, ovine, guinea pig, and rabbit Aβ40 peptide. Besides the TFA salt, Bachem offers the HCl salt of the peptide. The inverted sequence, can be used as inactive control in experiments employing Aβ 1-40. For detailed descriptions of the preparation of wild-type and mutant Aβ 1-40 monomers and protofibrils please see the paper of Jan, Hartley, and Lashuel.

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