转录因子SOX-11蛋白重组兔单克隆抗体

别    名 SRY (sex determining region Y) box 11; SRY related HMG box gene 11; Transcription factor SOX-11; SOX11_HUMAN.   

研究领域 肿瘤  细胞生物  神经生物学  信号转导  干细胞  转录调节因子  表观遗传学   

抗体来源 Rabbit 

克隆类型 Monoclonal 

克 隆 号 1E8 

交叉反应 (predicted: Human, ) 

产品应用 WB=1:500-1000 IP=1:20-100 ICC=1:50-200 IF=1:50-200 

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user. 

分 子 量 47kDa 

细胞定位 细胞核  

性    状 Liquid 

浓    度 1mg/ml 

免 疫 原 Recombinant human SOX11 protein (1-100aa):  

亚    型 IgG 

纯化方法 affinity purified by Protein A 

储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 

保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 

PubMed PubMed 

产品介绍 This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008]

 

Function:

Transcriptional activator.

 

Subcellular Location:

Nucleus.

 

Tissue Specificity:

Mainly expressed in the developing central nervous system.

 

Similarity:

Contains 1 HMG box DNA-binding domain.

 

SWISS:

P35716

 

Gene ID:

6664

 

Database links:

Entrez Gene: 6664 HumanEntrez Gene: 20666 MouseEntrez Gene: 84046 RatOmim: 600898 HumanSwissProt: P35716 HumanSwissProt: Q7M6Y2 MouseSwissProt: P0C1G9 RatUnigene: 432638 HumanUnigene: 41702 MouseUnigene: 466344 MouseUnigene: 162854 Rat

 

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

 

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