多巴胺受体D1重组兔单克隆抗体

中文名称 多巴胺受体D1重组兔单克隆抗体 

别    名 DRD1; dopamine D1 receptor; D(1A) dopamine receptor; D1A dopamine receptor; Dopamine D1Receptors; D1DR; DADR; Dopamine Receptor D1; DR D1; DR D1A; DRD 1; DRD1 receptor; DRD1; DRD1A; DRD1_HUMAN; D(1A) dopamine receptor; DRD 1A; DRD1.   

研究领域 肿瘤  免疫学  神经生物学   

抗体来源 Rabbit 

克隆类型 Monoclonal 

克 隆 号 3C3 

交叉反应 (predicted: Human, Mouse, Rat, ) 

产品应用 WB=1:500-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user. 

分 子 量 50kDa 

细胞定位 细胞浆 细胞膜  

性    状 Liquid 

浓    度 1mg/ml 

免 疫 原 C-terminus human Dopamine Receptor D1:  

亚    型 IgG 

纯化方法 affinity purified by Protein A 

储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 

保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 

PubMed PubMed 

产品介绍 This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]

 

Function:

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

 

Subunit:

Interacts with DNAJC14 via its C-terminus. Interacts with DRD1IP.

 

Subcellular Location:

Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.

 

Tissue Specificity:

Detected in caudate, nucleus accumbens and in the olfactory tubercle.

 

Similarity:

Belongs to the G-protein coupled receptor 1 family.

 

SWISS:

P21728

 

Gene ID:

1812

 

Database links:

Entrez Gene: 1812 HumanEntrez Gene: 13488 MouseEntrez Gene: 24316 RatOmim: 126449 HumanSwissProt

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