 |
|
|||||||||||||||||||||||||||||||||
| [发表评论] [本类其他产品] [本类其他供应商] [收藏] | ||||||||||||||||||||||||||||||||||
| 销售商： 上海雅吉生物科技有限公司 | 查看该公司所有产品 >> |
| 英文名称 | AIF1 (9A3) |
| 中文名称 | 离子钙接头蛋白单克隆抗体 |
| 别 名 | AIF 1; AIF1; AIF1 protein; IBa1; iba-1; IBa 1; allograft inflammatory factor 1; Allograft inflammatory factor 1 splice variant G; balloon angioplasty responsive transcription; BART 1; G1; G1 putative splice variant of allograft inflamatory factor 1; IBA 1; IBA1; interferon gamma responsive transcript; Ionized calcium binding adapter molecule 1; ionized calcium-binding adapter molecule; IRT 1; IRT1; Microglia response factor; MRF1; Protein G1. |
| 研究领域 | 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Monoclonal |
| 克 隆 号 | 9A3 |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | WB=1:500 IP=1:10-50 IHC-P=1:100-500 ICC=1:50-100 IF=1:50-100 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 17kDa |
| 细胞定位 | 细胞浆 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human AIF1:100-147/147 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | Allograft Inflammatory Factor-1 (AIF1)or ionized calcium-binding adaptor molecule 1 (Iba1) is expressed selectively in microglia/macrophages and is a Ca2+-binding peptide produced by activated monocytes and microglial cells. It has been suggested that AIF1 expression is associated with chronic inflammatory processes. AIF1 is expressed by activated monocytes and might participate in a variety of pathogenic processes in the mammalian brain and in chronic transplant rejection. It has been shown to be expressed early and persistently in chronically rejecting cardiac allografts but not in cardiac syngrafts and host hearts. Function: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. Subunit: Homodimer (Potential). Monomer. Interacts with LCP1. Subcellular Location: Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. Tissue Specificity: Detected in T-lymphocytes and peripheral blood mononuclear cells. Similarity: Contains 2 EF-hand domains. SWISS: P55008 Gene ID: 199 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品图片 |  Sample: Lane 1: Lung (Rat) Lysate at 40 ug Lane 2: Lung (Mouse) Lysate at 40 ug Lane 3: Spleen (Rat) Lysate at 40 ug Lane 4: Spleen (Mouse) Lysate at 40 ug Lane 5: Lymph node (Rat) Lysate at 40 ug Lane 6: Lymph node (Mouse) Lysate at 40 ug Lane 7: Bone (Rat) Lysate at 40 ug Lane 8: Bone (Mouse) Lysate at 40 ug Lane 9: Cerebrum (Rat) Lysate at 40 ug Lane 10: U937 (Human) Cell Lysate at 30 ug Primary: Anti-AIF1 (bsm-54132R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 17 kD Observed band size: 17 kD  Sample: Lane 1: U937 (Human) Cell Lysate at 30 ug Lane 2: Spleen (Mouse) Lysate at 40 ug Lane 3: Spleen (Rat) Lysate at 40 ug Lane 4: Lymph node (Mouse) Lysate at 40 ug Lane 5: Lymph node (Rat) Lysate at 40 ug Lane 6: Bone (Mouse) Lysate at 40 ug Lane 7: Bone (Rat) Lysate at 40 ug Lane 8: Cerebrum (Mouse) Lysate at 40 ug Lane 9: Cerebrum (Rat) Lysate at 40 ug Primary: Anti-AIF1 (bsm-54132R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 17 kD Observed band size: 15 kD |
试剂盒售后：本公司出售的试剂盒均保质保量，质量问题均可免费退换，另提供免费代测服务。
细胞售后：
1. 细胞运输丢失、瓶身破损、培养液严重漏液等，重发；
3. 细胞收到当天以及第2,3天请拍照，未告知的视为产品合格。4-10天内出现问题，请提供细胞照片和细胞出现问题的照片以及细胞相关操作的详细步骤，并跟我公司人员及时沟通判定是否重发，具体可以参照我官网或者随货说明书相关售后条款。
细胞售后：
1. 细胞运输丢失、瓶身破损、培养液严重漏液等，重发；
3. 细胞收到当天以及第2,3天请拍照，未告知的视为产品合格。4-10天内出现问题，请提供细胞照片和细胞出现问题的照片以及细胞相关操作的详细步骤，并跟我公司人员及时沟通判定是否重发，具体可以参照我官网或者随货说明书相关售后条款。
手机版：离子钙接头蛋白单克隆抗体
Copyright(C) 1998-2025 生物器材网 电话：021-64166852;13621656896 E-mail：info@bio-equip.com