重组SARS-CoV-2 S1蛋白(无标签)(＞85%)

特别提示：包括重组SARS-CoV-2 S1蛋白(无标签)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组SARS-CoV-2 S1蛋白(无标签)
英文名称：Recombinant SARS-CoV-2 S1 Protein (non-tag)
产品货号：JN2085
产品规格：50μg|500μg|1mg

本制品由哺乳动物表达系统制备，目的基因编码表达SARS-CoV-2 S1 Protein(Gln14-Arg685)，用作免疫原或标准品。

Accession#：QHD43416.1
分子量：78.3kDa
实测分子量：100-130kDa（还原条件下）
纯度：＞85%（还原性SDS-PAGE）
纯化方式：亲和色谱法
贮存液：PBS，pH7.4，0.2μm过滤
保存条件：-20℃。

生物活性：


Immobilized SARS-CoV-2 S1 Protein (Cat#JN2085) at 2μg/ml (100μl/well) can bind Human ACE-2-Fc(Cat#JN2061).The ED₅₀of Human ACE-2-Fc(Cat#JN2061) is 49ng/ml.



Immobilized Human ACE-2-Fc(Cat#JN2061) at 10μg/ml (100μl/well) can bind SARS-CoV-2 S1 Protein (Cat#JN2085):Biotinylated by NHS-biotin prior to testing.The ED₅₀of SARS-CoV-2 S1 Protein (Cat#JN2085)is 1.18μg/ml.

背景资料：
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation,apoptosis,cancer development and progression,and the innate immune response.Known receptors bind S1 are ACE2,angiotensin-converting enzyme 2,DPP4,CEACAM etc..The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process.Most notable is severe acute respiratory syndrome (SARS).The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion.It is also a major immunogen and a target for entry inhibitors.It"s been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor.The spike protein is a large type I transmembrane protein containing two subunits,S1 and S2.S1 mainly contains a receptor binding domain (RBD),which is responsible for recognizing the cell surface receptor.S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses,as well as protective immunity.

根据您的关注的重组SARS-CoV-2 S1蛋白(无标签)(＞85%)，重组SARS-CoV-2 S1 Protein (non-tag)，重组新冠病毒S1蛋白，Recombinant SARS-CoV-2 S1 Protein (non-tag)，重组无标签，重组新型冠状病毒S1蛋白，重组SARS-CoV-2 S1蛋白，您可能还对以下产品有需求：


JN1931 重组人脂肪酸结合蛋白3(FABP3) 10μg|50μg|500μg|1mg
JN0590 重组人非转移性黑色素瘤糖蛋白B(GPNMB) 10μg|50μg|500μg|1mg
JN0876 重组人WIBG 10μg|50μg|500μg|1mg
JN0988 重组人胞质磺基转移酶家族1B成员1(SULT1B1) 10μg|50μg|500μg|1mg
JN1130 重组人胶质细胞源性神经营养因子(GDNF) 10μg|50μg|500μg|1mg
JN1690 重组人Cathepsin Z(组织蛋白酶Z)(溶酶体半胱氨酸蛋白酶) 10μg|50μg|500μg|1mg
JN1753 重组人半胱氨酸蛋白酶ATG4C(自噬相关蛋白酶ATG4C) 10μg|50μg|500μg|1mg

关注重组SARS-CoV-2 S1蛋白(无标签)(＞85%)，重组SARS-CoV-2 S1 Protein (non-tag)，重组新冠病毒S1蛋白，Recombinant SARS-CoV-2 S1 Protein (non-tag)，重组无标签，重组新型冠状病毒S1蛋白，重组SARS-CoV-2 S1蛋白的同时，为您推荐更多您可能感兴趣的产品：



名称：重组小鼠白介素IL-6(白细胞介素6)
货号：JN0368
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Phe25-Thr211表达纯化而来。

IL-6质量控制：＞95%(还原性SDS-PAGE)。

IL-6制剂：冻干品

IL-6保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-6复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-6：
Interleukin-6 (IL-6) is a pro-inflammatory cytokine that also has an important role in immunity. Mouse IL-6 appears to be directly involved in the responses that occur after infection and injury and may prove to be as important as IL-1 in regulating the acute phase response. Mouse IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. IL-6 has a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, nerve cells differentiation in hepatocytes, and acute phase reactants.

北京百奥莱博科技有限公司一家专注于生命科学研究领域的生物技术公司，坚持“质量至上，服务为本，全心全意助力生命科学”的理念，为广大用于提供稳定、可靠、专业的产品和服务支持，产品线包括分子生物学，细胞生物学，免疫检测，抗体，重组蛋白，血液制品等系列。“忙忙碌碌的平凡，铸就事业的不凡”。让我们携起手来，共同创造生命科学的蓬勃发展。