特别提示:包括重组SARS-CoV-2 S1蛋白(Fc标签)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组SARS-CoV-2 S1蛋白(Fc标签)
英文名称:Recombinant SARS-CoV-2 S1 Protein (C-Fc)
产品货号:JN2087
产品规格:50μg|500μg|1mg
本制品由哺乳动物表达系统制备,目的基因编码表达SARS-CoV-2 S1 Protein(Gln14-Arg685),C端带有一个Fc标签,用作免疫原或标准品。
Accession#:QHD43416.1
分子量:102.2kDa
实测分子量:130-140kDa(还原条件下)
纯度:>90%(还原性SDS-PAGE)
纯化方式:亲和色谱法
贮存液:PBS,pH7.4,0.2μm过滤
保存条件:-20℃。
生物活性:
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Immobilized Human ACE-2-Fc(CAT#JN2061) at 10μg/ml (100μl/well) can bind SARS-CoV-2 S1 Protein-Fc (Cat#JN2087).The ED
50of SARS-CoV-2 S1 Protein-Fc (Cat#JN2087) is 850ng/mL.
背景资料:
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation,apoptosis,cancer development and progression,and the innate immune response.Known receptors bind S1 are ACE2,angiotensin-converting enzyme 2,DPP4,CEACAM etc..The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process.Most notable is severe acute respiratory syndrome (SARS).The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion.It is also a major immunogen and a target for entry inhibitors.It"s been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor.The spike protein is a large type I transmembrane protein containing two subunits,S1 and S2.S1 mainly contains a receptor binding domain (RBD),which is responsible for recognizing the cell surface receptor.S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses,as well as protective immunity.
根据您的关注的
重组SARS-CoV-2 S1蛋白(Fc标签)(>90%),Recombinant SARS-CoV-2 S1 Protein (C-Fc),重组Fc标签,重组新型冠状病毒S1蛋白,重组SARS-CoV-2 S1 Protein (C-Fc),重组新冠病毒S1蛋白,重组SARS-CoV-2 S1蛋白,您可能还对以下产品有需求:
名称:重组人成纤维细胞生长因子8F(FGF-8F)
货号:JN0270
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Gln23-Arg244在N端含有His标签
FGF-8f质量控制:>95%(还原性SDS-PAGE)。
FGF-8f制剂:冻干品
FGF-8f保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
FGF-8f复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于FGF-8f:
Fibroblast growth factor 8 (FGF8) is a member of the fibroblast growth factor family. It is discovered as a growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells. Mouse FGF8b shares 100% aa identity with human FGF8b. FGF8 is widely expressed during embryogenesis, and mediates epithelial-mesenchymal transitions. It plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. It is required for normal brain, eye, ear, limb development during embryogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system.
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关注
重组SARS-CoV-2 S1蛋白(Fc标签)(>90%),Recombinant SARS-CoV-2 S1 Protein (C-Fc),重组Fc标签,重组新型冠状病毒S1蛋白,重组SARS-CoV-2 S1 Protein (C-Fc),重组新冠病毒S1蛋白,重组SARS-CoV-2 S1蛋白的同时,为您推荐更多您可能感兴趣的产品:
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