重组SARS-CoV-2 S-RBD（mFc标签）(＞95%)

特别提示：包括重组SARS-CoV-2 S-RBD（mFc标签）在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组SARS-CoV-2 S-RBD（mFc标签）
英文名称：Recombinant SARS-CoV-2 Spike Protein RBD(C-mFc)
产品货号：JN2082
产品规格：50μg|500μg|1mg

本制品由哺乳动物表达系统制备，目的基因编码表达SARS-CoV-2 Spike Protein RBD(Asn331-Val524)，C端带有一个mFc标签，用作免疫原或标准品。

Accession#：QHD43416.1
分子量：47.9kDa
纯度：＞95%（还原性SDS-PAGE）
纯化方式：亲和色谱法
贮存液：PBS，pH7.4，0.2μm过滤
保存条件：-20℃。

生物活性：

Immobilized Human ACE-2-His(货号：JN0552) at 10μg/ml (100μl/well) can bind SARS-CoV-2 Spike Protein RBD(货号：JN2082).The ED₅₀of SARS-CoV-2 Spike Protein RBD(货号：JN2082) is 62ng/ml.

背景资料：
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation,apoptosis,cancer development and progression,and the innate immune response.Known receptors bind S1 are ACE2,angiotensin-converting enzyme 2,DPP4,CEACAM etc..The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process.Most notable is severe acute respiratory syndrome (SARS).The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion.It is also a major immunogen and a target for entry inhibitors.It"s been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor.The spike protein is a large type I transmembrane protein containing two subunits,S1 and S2.S1 mainly contains a receptor binding domain (RBD),which is responsible for recognizing the cell surface receptor.S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses,as well as protective immunity.

根据您的关注的重组SARS-CoV-2 S-RBD（mFc标签）(＞95%)，重组SARS-CoV-2 S-RBD，Recombinant SARS-CoV-2 Spike Protein RBD(C-mFc)，重组新型冠状病毒刺突蛋白受体结合域，重组新冠病毒S蛋白RBD，重组mFc标签，重组SARS-CoV-2 Spike Protein RBD(C-mFc)，重组SARS-CoV-2受体结合域，您可能还对以下产品有需求：



名称：重组人成纤维生长因子4
货号：JN0281
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Ser54-Leu206表达纯化而来。

FGF-4质量控制：＞95%(还原性SDS-PAGE)。

FGF-4制剂：冻干品

FGF-4保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

FGF-4复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于FGF-4：
Fibroblast growth factor 4(FGF-4) is a heparin binding member of the FGF family. The human FGF4 cDNA encodes 206 amino acids (aa) with a 33 aa signal sequence and a 173 aa mature protein with an FGF homology domain that contains a heparin binding region near the C-terminus. Mature human FGF4 shares 91%, 82%, 94% and 91% aa identity with mouse, rat, canine and bovine FGF4, respectively. Human FGF-4 has been shown to exhibit cross species activity. Expression of FGF-4 and its receptors, FGF R1c, 2c, 3c and 4, is spatially and temporally regulated during embryonic development. FGF-4 is proposed to play a physiologically relevant role in human embryonic stem cell selfrenewal. It promotes stem cell proliferation, but may also aid differentiation depending on context and concentration, and is often included in embryonic stem cell media in vitro. FGF-4 is mitogenic for fibroblasts and endothelial cells in vitro and has autocrine transforming potential. It is a potent angiogenesis promoter in vivo and has been investigated as therapy for coronary artery disease.

关注重组SARS-CoV-2 S-RBD（mFc标签）(＞95%)，重组SARS-CoV-2 S-RBD，Recombinant SARS-CoV-2 Spike Protein RBD(C-mFc)，重组新型冠状病毒刺突蛋白受体结合域，重组新冠病毒S蛋白RBD，重组mFc标签，重组SARS-CoV-2 Spike Protein RBD(C-mFc)，重组SARS-CoV-2受体结合域的同时，为您推荐更多您可能感兴趣的产品：


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北京百奥莱博科技有限公司一家专注于生命科学研究领域的生物技术公司，坚持“质量至上，服务为本，全心全意助力生命科学”的理念，为广大用于提供稳定、可靠、专业的产品和服务支持，产品线包括分子生物学，细胞生物学，免疫检测，抗体，重组蛋白，血液制品等系列。“忙忙碌碌的平凡，铸就事业的不凡”。让我们携起手来，共同创造生命科学的蓬勃发展。