特别提示:包括兔抗人表皮生长因子抗体在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:兔抗人表皮生长因子抗体
英文名称:Anti-human EGF Antibody
产品货号:Q50004
产品规格:100μL|200μL|400μL
交叉反应:人
特异性:人EGF
免疫原:重组人EGF
宿主:兔
克隆性:多克隆
抗体类型:兔IgG
纯化方式:蛋白A纯化
制剂:液体
缓冲液:0.2μm filtered solution in PBS
保存条件:-20℃,避免反复冻融
蛋白全称:epidermal growth factor
推荐应用:
应用 |
推荐稀释比例 |
ELISA |
1:1000-1:2000 |
制备方法:
Produced in rabbits immunized with purified,recombinant Human EGF/Epidermal Growth Factor (rh EGF,Asn971-Arg1023).Total IgG was purified by Protein A affinity chromatography.
背景资料:
EGF is the founding member of the EGF-family of proteins.Members of this protein family have highly similar structural and functional characteristics.EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats.Human EGF is a 645-Da protein with 53 amino acid residues and three intramolecular disulfide bonds.As a low-molecular-weight polypeptide,EGF was first purified from the mouse submandibular gland,but since then it was found in many human tissues including submandibular gland,parotid gland.It can also be found in human platelets,macrophages,urine,saliva,milk,and plasma.EGF is a growth factor that stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture.It results in cellular proliferation,differentiation,and survival.Salivary EGF,which seems also regulated by dietary inorganic iodine,also plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity.EGF acts by binding with high affinity to epidermal growth factor receptor on the cell surface and stimulating the intrinsic protein-tyrosine kinase activity of the receptor.The tyrosine kinase activity,in turn,initiates a signal transduction cascade that results in a variety of biochemical changes within the cell - a rise in intracellular calcium levels,increased glycolysis and protein synthesis,and increases in the expression of certain genes including the gene for EGFR - that ultimately lead to DNA synthesis and cell proliferation.
根据您的关注的
兔抗人表皮生长因子抗体,兔抗人EGF多抗,您可能还对以下产品有需求:
名称:阴离子交换蛋白2抗体
货号:K10642
规格:0.1ml|0.2ml
宿主物种:兔
交叉反应:人
克隆类型:多克隆
分 子 量:137kDa
浓 度:1mg/1ml
亚 型:IgG
细胞定位:细胞膜
免 疫 原:KLH conjugated synthetic peptide derived from human AE2/SLC4
纯化方法:蛋白A亲和纯化
产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复)
尚未测试其他应用;
实际稀释浓度可根据用户的具体用途决定。
储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件:4℃运输,-20℃保存,避免反复冻融
应用领域:肿瘤 心血管 细胞生物 通道蛋白
名称:周期素B3抗体
货号:K12272
规格:0.1ml|0.2ml
宿主物种:兔
交叉反应:人,小鼠,大鼠,狗,猪,奶牛,马,绵羊
克隆类型:多克隆
分 子 量:158kDa
浓 度:1mg/1ml
亚 型:IgG
细胞定位:细胞核
免 疫 原:KLH conjugated synthetic peptide derived from human Cyclin B
纯化方法:蛋白A亲和纯化
产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
尚未测试其他应用;
实际稀释浓度可根据用户的具体用途决定。
储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件:4℃运输,-20℃保存,避免反复冻融
应用领域:细胞生物 染色质和核信号 细胞周期蛋白
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兔抗人表皮生长因子抗体,兔抗人EGF多抗的同时,为您推荐更多您可能感兴趣的产品:
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