重组人ACE2(Fc标签)(＞95%)

特别提示：包括重组人ACE2(Fc标签)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人ACE2(Fc标签)
英文名称：Recombinant Human ACE-2 (C-Fc)
产品货号：JN2061
产品规格：10μg|50μg|500μg|1mg

Recombinant Human Angiotensin-Converting Enzyme 2 is produced by our Mammalian expression system and the target gene encoding Gln18-Ser740 is expressed with a Fc tag at the C-terminus.

制剂：Lyophilized from a 0.2μm filtered solution of 20mM Tris-HCl,300mM NaCl,1mM ZnCl2,10% Glycerol,pH7.4.
纯度：＞95% as determined by reducing SDS-PAGE.
内毒素：＜0.1ng/μg (1 EU/μg) as determined by LAL test.
生物活性：

Immobilized Human ACE-2(Fc Tag)(Cat#JN2061) at 10μg/ml (100μl/well) can bind SARS-CoV-2 S Protein RBD-SD1-mFc(Cat#JN2088).The ED₅₀of Recombinant SARS-CoV-2 S Protein RBD-mFc(Cat#JN2088) is 15.5ng/ml。

保存条件：-20℃，有效期6个月，避免反复冻融。

背景资料：
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family,the ACE family includes somatic and germinal ACE.ACE-2 cleaves angiotensins I and II as a carboxypeptidase,ACE-2 converts angiotensin I to angiotensin 1-9,and angiotensin II to angiotensin 1-7.ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency.ACE-2 can be high expressed in testis,kidney and heart,in colon,small intestine and ovary at moderate levels.Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity.ACE-2 may play an important role in regulating the heart function.

根据您的关注的重组人ACE2(Fc标签)(＞95%)，rACE2，重组人ACE-2 (C-Fc)，重组ACE-2 (C-Fc)，rhACE2，重组人血管紧张素转换酶2，Recombinant Human ACE-2 (C-Fc)，重组人ACE2，重组ACE2，重组Fc标签，重组人ACE-2，重组人Fc标签，重组人血管紧张素转化酶2，您可能还对以下产品有需求：


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关注重组人ACE2(Fc标签)(＞95%)，rACE2，重组人ACE-2 (C-Fc)，重组ACE-2 (C-Fc)，rhACE2，重组人血管紧张素转换酶2，Recombinant Human ACE-2 (C-Fc)，重组人ACE2，重组ACE2，重组Fc标签，重组人ACE-2，重组人Fc标签，重组人血管紧张素转化酶2的同时，为您推荐更多您可能感兴趣的产品：



名称：重组小鼠趋化因子CXCL16(SR-PSOX)
货号：JN0315
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Asn27-Trp201在C端含有His标签。

CXCL16/SR-PSOX质量控制：＞95%(还原性SDS-PAGE)。

CXCL16/SR-PSOX制剂：冻干品

CXCL16/SR-PSOX保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

CXCL16/SR-PSOX复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于CXCL16/SR-PSOX：
CXCL16 is a single-pass type I membrane protein, which consists of 246 amino acids, CXCL16 induces a strong chemotatic response and calcium mobilization. CXCL16 acts as a scavenger receptor on macrophages, which specially binds to oxidized low density lipoprotein. CXCL16 may involves in pathophysiology such as atherogenesis. Soluble CXCL16 may play an important role in liver metastases through the induction of epithelial-mesenchymal transition.

名称：重组人白介素1受体α(IL-1Rα)
货号：JN0340
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Arg26-Glu177表达纯化而来。

IL-1F3/IL-1Ra质量控制：＞95%(还原性SDS-PAGE)。

IL-1F3/IL-1Ra制剂：冻干品

IL-1F3/IL-1Ra保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-1F3/IL-1Ra复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-1F3/IL-1Ra：
Interleukin-1 Receptor Antagonist (IL-1RN) is a member of the IL-1 family. Endogenous IL-1RN is produced in numerous animal disease models as well as in human autoimmune and chronic inflammatory diseases. It binds to IL-1 receptors in competition with IL-1, but does not elicit intracellular response from this binding. Its role in counteracting the proinflammatory effects of IL-1 is being studied by numerous research groups. IL-4 and IL-13 have been shown to amplify the stimulatory effect of IL1-beta on the production of soluble and intracellular forms of IL-1RN. The regulated expression of IL-1RN in various cell types has been shown to be influenced by cytokines. In synovial fibroblasts, IL-1, TNF-alpha, or PDGF markedly enhances the synthesis of IL-1RN.

北京百奥莱博科技有限公司一家专注于生命科学研究领域的生物技术公司，坚持“质量至上，服务为本，全心全意助力生命科学”的理念，为广大用于提供稳定、可靠、专业的产品和服务支持，产品线包括分子生物学，细胞生物学，免疫检测，抗体，重组蛋白，血液制品等系列。“忙忙碌碌的平凡，铸就事业的不凡”。让我们携起手来，共同创造生命科学的蓬勃发展。