特别提示:包括重组SARS-CoV-2 S2蛋白(Fc标签)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组SARS-CoV-2 S2蛋白(Fc标签)
英文名称:Recombinant SARS-CoV-2 S2 Protein (C-Fc Tag)
产品货号:JN2098
产品规格:1mg
本制品由哺乳动物表达系统制备,目的基因编码表达SARS-CoV-2 S蛋白S2亚单位(Ser686-Gln1208),C端带有一个Fc标签,用作免疫原或标准品。
Accession#:QHD43416.1
分子量:84.1kDa
实测分子量:100-130kDa(还原条件下)
纯度:>95%(还原性SDS-PAGE)
纯化方式:亲和色谱法
贮存液:PBS,pH7.4,0.2μm过滤
保存条件:-20℃。
背景资料:
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation,apoptosis,cancer development and progression,and the innate immune response.Known receptors bind S1 are ACE2,angiotensin-converting enzyme 2,DPP4,CEACAM etc..The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process.Most notable is severe acute respiratory syndrome (SARS).The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion.It is also a major immunogen and a target for entry inhibitors.It"s been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor.The spike protein is a large type I transmembrane protein containing two subunits,S1 and S2.S1 mainly contains a receptor binding domain (RBD),which is responsible for recognizing the cell surface receptor.S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses,as well as protective immunity.
根据您的关注的
重组SARS-CoV-2 S2蛋白(Fc标签)(>95%),重组SARS-CoV-2 S2蛋白,重组新型冠状病毒S蛋白S2亚单位,重组SARS-CoV-2 S2 Protein (C-Fc Tag),重组新型冠状病毒S2蛋白,Recombinant SARS-CoV-2 Spike glycoprotein subunit 2,Recombinant SARS-CoV-2 S2 Protein (C-Fc Tag),重组Fc标签,重组新冠病毒Spike蛋白S2亚基,重组SARS-CoV-2 S蛋白S2亚单位,您可能还对以下产品有需求:
名称:重组人GM-CSF(哺乳动物表达)(含His标签)
货号:JN0207
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备,目的基因编码的Ala18-Glu144在C端含有His标签。
GM-CSF质量控制:>95%(还原性SDS-PAGE)。
GM-CSF制剂:冻干品
GM-CSF保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
GM-CSF复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于GM-CSF:
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has a functional role on non-hematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines.
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关注
重组SARS-CoV-2 S2蛋白(Fc标签)(>95%),重组SARS-CoV-2 S2蛋白,重组新型冠状病毒S蛋白S2亚单位,重组SARS-CoV-2 S2 Protein (C-Fc Tag),重组新型冠状病毒S2蛋白,Recombinant SARS-CoV-2 Spike glycoprotein subunit 2,Recombinant SARS-CoV-2 S2 Protein (C-Fc Tag),重组Fc标签,重组新冠病毒Spike蛋白S2亚基,重组SARS-CoV-2 S蛋白S2亚单位的同时,为您推荐更多您可能感兴趣的产品:
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