特别提示:包括小鼠抗ERO1L单克隆抗体在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:小鼠抗ERO1L单克隆抗体
英文名称:ERO1L Antibody
产品货号:P11002
产品规格:50μL|100μL|150μL
宿主:小鼠
种属反应性:人、小鼠、大鼠
抗体类型:IgG2b
纯化方法:蛋白A纯化
浓度:1μg/μL
贮存液:PBS,50%甘油,含防腐剂
保存温度:-20℃
推荐应用及稀释比例:
应用 |
说明 |
WB |
1:5000~50000 |
IHC |
1:500~2000 |
蛋白别名:
ERO1 alpha
ERO1L
ERO1L alpha
ERO1 like (S.cerevisiae)
ERO1 like protein alpha
ERO1L
ERO1L相关说明:
ERO1L,also named as ERO1-alpha,is an essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds.It acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange.It does not act as a direct oxidant of folding substrate,but relies on P4HB/PDI to transfer oxidizing equivalent.Associates with ERP44 but not with GRP54,demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins.Its reoxidation probably involves electron transfer to molecular oxygen via FAD.Glutathione may be required to regulate its activity in the endoplasmic reticulum.It may be responsible for a significant proportion of reactive oxygen species (ROS) in the cell,thereby being a source of oxidative stress.It is required for the folding of immunoglobulin proteins.Responsible for the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae,thereby playing a role in retrotranslocation of the toxin.
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关注
小鼠抗ERO1L单克隆抗体,ERO1α抗体,ERO1A抗体的同时,为您推荐更多您可能感兴趣的产品:
名称:活化转录因子1抗体
货号:K10053
规格:0.1ml|0.2ml
宿主物种:兔
交叉反应:人,小鼠,大鼠
克隆类型:多克隆
分 子 量:29kDa
浓 度:1mg/1ml
亚 型:IgG
细胞定位:细胞核
免 疫 原:KLH conjugated synthetic peptide derived from human ATF1
纯化方法:蛋白A亲和纯化
产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
尚未测试其他应用;
实际稀释浓度可根据用户的具体用途决定。
储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件:4℃运输,-20℃保存,避免反复冻融
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货号:K10857
规格:0.1ml|0.2ml
宿主物种:兔
交叉反应:人,小鼠,大鼠,狗,猪,马,绵羊
克隆类型:多克隆
分 子 量:41kDa
浓 度:1mg/1ml
亚 型:IgG
细胞定位:细胞浆
免 疫 原:KLH conjugated synthetic peptide derived from human ABLIM3
纯化方法:蛋白A亲和纯化
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尚未测试其他应用;
实际稀释浓度可根据用户的具体用途决定。
储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件:4℃运输,-20℃保存,避免反复冻融
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