重组SARS-CoV-2 NSP1蛋白(His标签)(＞85%)

特别提示：包括重组SARS-CoV-2 NSP1蛋白(His标签)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组SARS-CoV-2 NSP1蛋白(His标签)
英文名称：Recombinant SARS-CoV-2 Non-structural Protein 1 (C-6*His Tag)
产品货号：JN2066
产品规格：10μg|50μg

本制品由E.coli表达系统制备，目的基因编码表达SARS-CoV-2 NSP1(Met1-Gly180)，C端包含一个6*His标签。

Accession#：YP_009725297.1

蛋白别名：SARS-CoV 2 nsp1;SARS-CoV 2 Leader protein

贮存液：20mM Tris-HCl,150mM NaCl,10% Glycerol,pH8.5（0.2μm过滤）

质量控制：
分子量：22.7kDa
实测分子量：25kDa（还原条件下）
纯度：＞85%（还原SDS-PAGE）

保存条件：-20℃，可稳定保存6个月，应避免反复冻融。

背景资料：
The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped,positive-stranded RNA viruses that can cause a severe respiratory disease.Its genome consists of a～30 kb linear,non-segmented,capped,polycistronic,polyadenylated RNA molecule,the first two-third of which is directly translated into two large polyproteins.These two polypeptides are processed into 16 non-structural proteins (nsps),forming the replicase complex,which is active in the cytoplasm in close association with cellular membranes.Nsp1 was proved to be able to suppress host gene expression by promoting host mRNA degradation and was involved in cellular chemokine deregulation.This virus evades the host innate immune response in part through the expression of its non-structural protein (nsp) 1,which inhibits both host gene expression and virus- and interferon (IFN)-dependent signaling.Thus,nsp1 is a promising target for drugs,as inhibition of nsp1 would make SARS-CoV more susceptible to the host antiviral defenses.

根据您的关注的重组SARS-CoV-2 NSP1蛋白(His标签)(＞85%)，重组SARS-CoV 2 Leader protein

贮存液：20mM Tris-HCl,150mM NaCl,10% Glycerol,pH8，重组SARS-CoV-2非结构蛋白1，重组SARS-CoV-2 NSP1蛋白，重组SARS-CoV 2 nsp1，重组新型冠状病毒NSP1蛋白，重组SARS-CoV-2 Non-structural Protein 1 (C-6*His Tag)，Recombinant SARS-CoV-2 Non-structural Protein 1 (C-6*His Tag)，重组His标签，重组新冠病毒NSP1蛋白，您可能还对以下产品有需求：



名称：重组人肿瘤坏死因子配体超家族成员15(TNFSF15)
货号：JN0439
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Leu192表达纯化得来。

TNFSF15质量控制：＞95%(还原性SDS-PAGE)


TNFSF15制剂：冻干品

TNFSF15保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TNFSF15复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TNFSF15：
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial cells. TNFSF15 is also able to regulate the expression of several important genes involved in angiogenesis. These findings are consistent with the view that TNFSF15 functions as an autocrine cytokine to inhibit angiogenesis and stabilize the vasculature.

关注重组SARS-CoV-2 NSP1蛋白(His标签)(＞85%)，重组SARS-CoV 2 Leader protein

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北京百奥莱博科技有限公司一家专注于生命科学研究领域的生物技术公司，坚持“质量至上，服务为本，全心全意助力生命科学”的理念，为广大用于提供稳定、可靠、专业的产品和服务支持，产品线包括分子生物学，细胞生物学，免疫检测，抗体，重组蛋白，血液制品等系列。“忙忙碌碌的平凡，铸就事业的不凡”。让我们携起手来，共同创造生命科学的蓬勃发展。