重组SARS-CoV-2 S-RBD-SD1(mFc标签)(＞95%)

特别提示：包括重组SARS-CoV-2 S-RBD-SD1(mFc标签)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组SARS-CoV-2 S-RBD-SD1(mFc标签)
英文名称：Recombinant SARS-CoV-2 Spike Protein RBD-SD1(C-mFc)
产品货号：JN2088
产品规格：50μg|500μg|1mg

本制品由哺乳动物表达系统制备，目的基因编码表达SARS-CoV-2 S-RBD-SD1(Arg319-Pro589)，C端带有一个mFc标签，用作免疫原或标准品。

技术指标：
Accession#：QHD43416.1
分子量：57kDa
实测分子量：60-80kDa（还原条件下）
纯度：＞95%（还原性SDS-PAGE，SEC-HPLC）
纯化方式：亲和色谱法
贮存液：PBS，pH7.4，0.2μm过滤
保存条件：-20℃。

SDS-PAGE：


SEC-HPLC：


生物活性：

Immobilized Human ACE-2(Cat#JN2061) at 2μg/ml (100μl/well) can bind Recombinant SARS-CoV-2 Spike Protein RBD-SD1 (Cat#JN2088),the ED₅₀ for this effect is 5-20ng/ml.

免疫反应：

Immobilized Anti-SARS-CoV-2 S1 mAb(Cat#JN4025) at 2μg/ml (100μl/well) can bind Recombinant SARS-CoV-2 Spike Protein RBD-SD1 (Cat#JN2088),the ED₅₀ for this effect is 5-20ng/ml.

批稳定性：

Batch stability is confirmed by binding ability with Anti-SARS-CoV-2 S1 mAb(Cat#JN4025) or ACE-2(Cat#JN2061).
The result showed that the batch variation is no significant differences among these samples.

冻融稳定性：

Freeze-thaw stability is confirmed by binding ability with Anti-SARS-CoV-2 S1 mAb(Cat#JN4025) or ACE-2(Cat#JN2061).


背景资料：
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation,apoptosis,cancer development and progression,and the innate immune response.Known receptors bind S1 are ACE2,angiotensin-converting enzyme 2,DPP4,CEACAM etc.The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process.Most notable is severe acute respiratory syndrome (SARS).The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion.It is also a major immunogen and a target for entry inhibitors.It"s been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor.The spike protein is a large type I transmembrane protein containing two subunits,S1 and S2.S1 mainly contains a receptor binding domain (RBD),which is responsible for recognizing the cell surface receptor.S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses,as well as protective immunity.

根据您的关注的重组SARS-CoV-2 S-RBD-SD1(mFc标签)(＞95%)，重组新型冠状病毒S-RBD-SD1，重组mFc标签，重组SARS-CoV-2 Spike Protein RBD-SD1(C-mFc)，Recombinant SARS-CoV-2 Spike Protein RBD-SD1(C-mFc)，重组SARS-CoV-2 S-RBD-SD1，重组新冠病毒S-RBD-SD1，您可能还对以下产品有需求：



名称：重组人CEACAM7(癌胚抗原相关细胞粘附分子7)
货号：JN0767
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Thr36-Phe142在C端含有His标签。

CEACAM7质量控制：＞95%(还原性SDS-PAGE)

CEACAM7制剂：冻干品

CEACAM7保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CEACAM7复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CEACAM7：
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7) is a member of the immunoglobulin superfamily A and CEA family. CEACAM7 localizes to the cell membrane and contains one Ig-like C2-type domain and one Ig-like V-type domain. The expression of CEACAM7 is significantly decreased in rectal cancer. Differences in CEACAM7 expression levels between long-term survivors and those with recurrent disease introduce a potential tumor marker to define a subset of patients who benefit most from adjuvant therapy.

关注重组SARS-CoV-2 S-RBD-SD1(mFc标签)(＞95%)，重组新型冠状病毒S-RBD-SD1，重组mFc标签，重组SARS-CoV-2 Spike Protein RBD-SD1(C-mFc)，Recombinant SARS-CoV-2 Spike Protein RBD-SD1(C-mFc)，重组SARS-CoV-2 S-RBD-SD1，重组新冠病毒S-RBD-SD1的同时，为您推荐更多您可能感兴趣的产品：

 

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北京百奥莱博科技有限公司一家专注于生命科学研究领域的生物技术公司，坚持“质量至上，服务为本，全心全意助力生命科学”的理念，为广大用于提供稳定、可靠、专业的产品和服务支持，产品线包括分子生物学，细胞生物学，免疫检测，抗体，重组蛋白，血液制品等系列。“忙忙碌碌的平凡，铸就事业的不凡”。让我们携起手来，共同创造生命科学的蓬勃发展。