重组SARS-CoV-2 Papain-like Protease

特别提示：包括重组SARS-CoV-2 Papain-like Protease在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组SARS-CoV-2 Papain-like Protease
英文名称：Recombinant SARS-CoV-2 Papain-like Protease
产品货号：JN2065
产品规格：10μg|50μg

本制品由E.coli表达系统制备，目的基因编码表达SARS-CoV-2 Papain-like Protease（Glu1564-Lys187）。

Accession #:QHD43415.1

蛋白别称：Papain-like Protease;PLpro;PL-PRO;pp1a;Replicase polyprotein 1a

贮存液：20mM Tris-HCl,10mM Mercaptoethanol [BME],20% Glycerol,pH7.5，0.2μm过滤


质量控制：

分子量：35.8kDa
实测分子量：34kDa（还原条件下）
纯度：＞90%（还原SDS-PAGE）

保存条件：-20℃，可稳定保存6个月，应避免反复冻融。


背景资料：
Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases,a chymotrypsin-like protease (3CLpro) and a papain-like protease (PLpro).These proteases are important targets for development of antiviral drugs that would inhibit viral replication and reduce mortality associated with outbreaks of SARS-CoV.PLpro is a cysteine protease located within the non-structural protein 3 (NS3) section of the viral polypeptide.PLPro activity is required to process the viral polyprotein into functional,mature subunits;specifically,PLPro cleaves a site at the amino-terminus of the viral replicase region.In addition to its role in viral protein maturation,PLPro possesses a deubiquitinating and deISGylating activity.In vivo,this protease antagonizes innate immunity by inhibiting IRF3-induced production of type I interferons.

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名称：重组人FGF2(碱性成纤维生长因子)
货号：JN0262
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Pro143-Ser288表达纯化而来。

FGF Basic质量控制：＞95%(还原性SDS-PAGE)。

FGF Basic制剂：冻干品

FGF Basic保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

FGF Basic复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于FGF Basic：
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family.The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells.

北京百奥莱博科技有限公司一家专注于生命科学研究领域的生物技术公司，坚持“质量至上，服务为本，全心全意助力生命科学”的理念，为广大用于提供稳定、可靠、专业的产品和服务支持，产品线包括分子生物学，细胞生物学，免疫检测，抗体，重组蛋白，血液制品等系列。“忙忙碌碌的平凡，铸就事业的不凡”。让我们携起手来，共同创造生命科学的蓬勃发展。