大鼠肝微粒体

    肝微粒体是体外研究一个化合物的代谢(酶抑制，清除率和代谢鉴定)以及药物-药物相互作用的主要工具。通常根据特定细胞色素酶的活性水平来选择微粒体。 
        
        
 

        齐氏生物提供的肝细胞微粒体来源于肝脏内质网膜的亚细胞组分。由肝细胞提取的每批产品都经过FDA推荐的方法，对肝细胞微粒体活性进行考察，然后于冻存管包装，20 mg/管；-80℃保存，干冰运输。

         用途：ADME及药代动力学检测试验

         种属：人/大鼠/小鼠/兔/狗/猪/猴  
        
         规格：0.5ml   20mg/ml

         运输：冻存管，干冰运输。


        微粒体产品被SCI论文引用（部分）：

1.Metabolism of chicoric acid by rat liver microsomes and bioactivity comparisons of chicoric acid and its metabolites
Q Liu, Y Wang, CX Xiao, W Wu, X Liu - Food & function, 2015 - pubs.rsc.org
… 11–14 Moreover, chicoric acid has showed anti-inflammatory, anti-bacterial, anti-HIV
activities, hypoglycemic and hepatocyte protective properties … Rat liver microsomes
were obtained from CHI Scientific, Inc. (Massachusetts, USA) 

 

2.Hypoxia-triggered gene therapy: a new drug delivery system to utilize photodynamic-induced hypoxia for synergistic cancer therapy
C Huang, J Zheng, D Ma, N Liu, C Zhu, J Li… - Journal of Materials …, 2018 - pubs.rsc.org
… Rat liver microsomes were purchased from CHI Scientific (Jiangsu China … under hypoxic conditions
(red curve); DDS in the presence of inactive rat liver microsomes and NADPH … 0 represent the
fluorescence intensity of TAMRA after and before rat liver microsome addition under …
 

附：产品介绍
 

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