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CD3
英文名称:CD3总访问:1893
国产/进口:半年访问:6
产地/品牌:湖南远泰生物技术有限公司产品类别:免疫学/诊断检测试剂
规       格: 最后更新:2004-2-1
货       号:
CAS   号:
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Mouse mAb to CD3
Clone CRIS-7
lsotype Mouse IgG2a
Source
A BALB/c mouse was immunized with stimulated human leucocytes. Splenocytes were fused with mouse myeloma NS 1 cells.
Specifications
The mAb CRIS-7 is characterized at Leucocyte typing 11 and 111 to be specific for the CD3 antigen of the TCRICD3 complex. Primary signals received trough this complex determine the specificity of immune reactions by selecting particular antigen/MHC-respon
Applications
The mAb CRIS-7 can be applied for specific detection of CD3 T lymphocytes in peripheral blood and in frozen and paraffin embedded tissue sections. The mAb is also capable to stimulate human PBMC both in soluble and particulate form resulting in hyperexpre
Frozen section +
Paraffin sections +
Flow cytometry +
ELISA n.d.
Blocking n.d.
Immuno-precipitation
Western blotting +
References
Alberola- Ila, J. et al., Stimulation through the TCR/CD3 complex up-regulates the CD2 surface expression on human T lymphocytes. J. Immunol. 146 : 1085 - 1092, (1991). McMichael, A.J. et al., Leucocyte typing III, Oxford University Press, Oxford, 1987.


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