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Ep-CAM
英文名称:Ep-CAM总访问:2137
国产/进口:半年访问:7
产地/品牌:湖南远泰生物技术有限公司产品类别:免疫学/诊断检测试剂
规       格: 最后更新:2004-2-1
货       号:
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参考报价:$2,000/株
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Mouse mAb to Ep-CAM
Clone VU1D9
lsotype Mouse IgG1-k
Source
A BALB/c mouse was immunized with NCI-H69 small cell lung carcinoma cells Splenocytes were fused with SP2/0 myeloma cells.
Specifications
EP-CAM (also called ESA, EGP40, 17- 1 A antigen, KSA, GA7333 -2) is a 40 kD epithelial protein expressed on baso-lateral cell surfaces in very many epithelial tissues (but absent from mesothelial tissues). The 324AA have 3 potential glycosylation sites an
Applications
It is the antibody of choice to differentiate between mesotheliorna and carcinoma, a common diagnostic problem. This was best shown sofar for the comparable BER- EP4 antibody (Gaffay et al., 1992). The antibody works well on paraffin sections, even withou
Frozen section +
Paraffin sections +
Flow cytometry +
ELISA +
Blocking +
Immuno-precipitation
Western blotting +
References
Tsubura et al., J Cutan. PathoL 19, 73 (1992) Herlyn et al., Hybridoma Suppl. 5, S3-S8 (1986). Szala et al., Proc. Nat. Acad. Sci. USA, 87, 3542-3546 (1990). Litvinov et al. J Cell. Biol. 125, 437-446 (1994). Gaffey et al., Amer. J Surg. Pathol. 16,
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