FK-506 生化试剂现货7折促销啦~绝对最低价！

浏览次数：3545　发布日期：2013-8-13　来源：本站　本站原创，转载请注明出处

产品名称：FK-506

化学名：Tacrolimus, fujimycin, Prograf, Advagraf, Protopic

CAS No： 104987-11-3

分子式：C44H69NO12

分子量：804.02

纯度：≥99%

溶解度：Soluble in DMSO or ethanol at 100 mg/mL; very poorly soluble in water;

保存：-20 ºC

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货号：abs810040

规格：大包装询价

货号产品名称规格

abs810040a FK-506 5mg

abs810040b FK-506 10mg

abs810040c FK-506 25mg

abs810040d FK-506 50mg

abs810040e FK-506 100mg

库存：现货

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生物活性：

FK-506 is an immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the

activity of the patient's immune system and so lower the risk of organ rejection. It is also used in a topical

preparation in the treatment of atopic dermatitis (eczema), severe refractory uveitis after bone marrow

transplants, exacerbations of minimal change disease, and the skin condition vitiligo. It reduces

interleukin-2 (IL-2) production by T-cells.

FK-506 reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP12 (FK506 binding

protein) creating a new complex. This FKBP12-FK506 complex interacts with and inhibits calcineurin thus

inhibiting both T-lymphocyte signal transduction and IL-2 transcription.

相关公司：爱必信（上海）生物科技有限公司
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