Naturethink 技术文章

184 次 EPAS1 通过内皮脂肪酸摄取减轻血流紊乱区域动脉粥样硬化的发生 2025-2-17
EPAS1 Attenuates Atherosclerosis Initiation at Disturbed Flow Sites Through Endothelial Fatty Acid UptakeKeywords: atherosclerosis; diet, high-fat; endothelial cells; obesity; plaq
184 次 NADPH 氧化酶4在缺氧条件下介导内皮功能 2025-2-17
NADPH Oxidase 4: Crucial for Endothelial Function under Hypoxia—Complementing ProstacyclinKeywords: NADPH oxidase 4; PTGIS; endothelial function; human endothelial cells; hyp
239 次人脐带间充质干细胞促进小胶质细胞中的细胞外基质重塑 2025-2-10
Human Umbilical Cord-Mesenchymal Stem Cells Promote Extracellular Matrix Remodeling in MicrogliaKeywords: extracellular matrix; human umbilical cord mesenchymal stem cells; microgl
209 次 Piezo1 通道通过介导机械应力诱导的铁内流来加剧髓核细胞的铁死亡 2025-2-10
Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influxSubject terms: Homeostasis, Pathogenesis机械应力可以有效地调节细胞
376 次 B细胞前体急性淋巴细胞白血病在骨髓间充质基质中引发干扰素α/β反应 2024-12-30
B-cell precursor acute lymphoblastic leukemia elicits an interferon-α/β response in bone marrow-derived mesenchymal stromaKWS：BCP-ALL；interferon-α/β；bone m
379 次机械力经靶向 SMAD1促巨噬细胞外泌体 UCHL3促进骨髓间充质干细胞成骨 2024-12-30
Mechanical force induces macrophage-derived exosomal UCHL3 promoting bone marrow mesenchymal stem cell osteogenesis by targeting SMAD1Keywords: Exosomes; Macrophages; Mechanical fo
213 次人牙龈成纤维细胞的成骨分化可抑制破骨细胞形成 2024-12-23
Osteogenic Differentiation of Human Gingival Fibroblasts Inhibits Osteoclast FormationKeywords: gingival fibroblasts; osteoblasts; osteoclastogenesis; osteoclasts; osteogenesis.牙龈
208 次循环牵张应力通过整合素αVβ3-肌动蛋白丝轴调控MSCs早期成骨分化 2024-12-23
Regulation of the integrin αVβ3- actin filaments axis in early osteogenic differentiation of human mesenchymal stem cells under cyclic tensile stressKeywords: Integrin &
574 次 FAK 通过 Drp1 调控心肌细胞线粒体裂变和功能 2024-12-16
FAK regulates cardiomyocyte mitochondrial fission and function through Drp1Keywords: Drp1; FAK; fibronectin; mitochondrial fission.线粒体对于心肌细胞的能量产生至关重要，其功能障碍与
711 次机械应力经TGF-β1 激活 Smad2/3 并抑制 NF-κB 以防软骨细胞焦亡 2024-12-16
Mechanical stress protects against chondrocyte pyroptosis through TGF-β1-mediated activation of Smad2/3 and inhibition of the NF-κB signaling pathway in an osteoarthriti
420 次动脉粥样硬化中血流紊乱会损害MerTK介导的主动脉内皮细胞的胞葬作用 2024-12-9
Disturbed flow impairs MerTK-mediated efferocytosis in aortic endothelial cells during atherosclerosisKeywords: Disturbed flow; MerTK; RNA-seq; atherosclerosis; efferocytosis; prot
401 次机械敏感的多囊蛋白1促进骨膜干/祖细胞在骨折愈合中的骨软骨分化 2024-12-9
Mechanosensitive protein polycystin-1 promotes periosteal stem/progenitor cells osteochondral differentiation in fracture healingKeywords: Fracture healing; Mechanical stress; Peri
404 次 TNFSF12/TWEAK调节结肠炎性成纤维细胞并促其与单核细胞相互作用 2024-12-2
The TNFSF12/TWEAK Modulates Colonic Inflammatory Fibroblast Differentiation and Promotes Fibroblast-Monocyte InteractionsKWS：TNFSF12/TWEAK；Colonic Inflammatory Fibroblast；Differ
385 次 miR-342-5p通过抑制 MYC增强内皮细胞对剪切力的动脉化响应 2024-12-2
miR-342-5p downstream to Notch enhances arterialization of endothelial cells in response to shear stress by repressing MYCKeywords: MT: Non-coding RNAs; Notch; arterialization; end
487 次激活的SIRT1 通过增强 H 型血管生成和骨形成的耦联来促进骨修复 2024-11-25
SIRT1 activation promotes bone repair by enhancing the coupling of type H vessel formation and osteogenesisKWS：SIRT1；bone repair；type H vessel formation；osteogenesis骨缺损可由感
623 次血管内皮细胞机械敏感基因在动脉粥样硬化形成和治疗中的研究进展 2024-11-25
Recent advances of mechanosensitive genes in vascular endothelial cells for the formation and treatment of atherosclerosisKeywords: Atherosclerosis; Blood flow; Endothelial cell; M
502 次 CD97 在压缩下通过 Rap1a/ERK 通路抑制破骨细胞分化 2024-11-18
CD97 inhibits osteoclast differentiation via Rap1a/ERK pathway under compressionSubject terms: Orthodontics, Cell signalling正畸治疗是通过正畸牙齿移动（OTM）矫正咬合不正。OTM 是一种
1070 次 Piezo1 介导的机械转导导致血流紊乱诱导的动脉粥样硬化内皮炎症 2024-11-18
Piezo1‐Mediated Mechanotransduction Contributes to Disturbed Flow‐Induced Atherosclerotic Endothelial InflammationKeywords: Piezo1; atherosclerosis; endothelial cells; inflammati
393 次绿茶化合物EGCG在子痫前期的体外静态和剪切应力模型中的抗氧化作用 2024-11-16
EGCG, a Green Tea Compound, Increases NO Production and Has Antioxidant Action in a Static and Shear Stress In Vitro Model of PreeclampsiaKeywords: EGCG; NO; antioxidant; endotheli
511 次电压门控性钙通道α2δ亚基-1调控结肠癌进展并影响其微环境 2024-10-28
CACNA2D1 regulates the progression and influences the microenvironment of colon cancerKeywords: CACNA2D1; Colon cancer; Fibroblast; Voltage-gated calcium channel; p53.近年来，由于化